| Home | Score | Away | League | Time (CST) |
|---|---|---|---|---|
| León | 0:1 | Atlas | Mexican Primera League | 09:00 |
| Cienciano | 0:0 | Melgar | Peruvian Primera Division | 09:00 |
| River Plate | 0:1 | Aldosivi | Copa Argentina | 08:45 |
| Nashville SC | 0:0 | Atlanta United | American Major League Soccer | 08:10 |
| Real Estelí | 0:0 | UNAN Managua | Nicaragua Primera Division | 09:00 |
| Fluminense | 1:1 | Bragantino | Brazilian Serie A | 07:00 |
| Fortaleza | 1:0 | Novorizontino | Brazilian Serie B | 08:00 |
| Londrina | 0:0 | Botafogo-SP | Brazilian Serie B | 08:00 |
| Bolívar | 1:0 | Guabirá | Bolivian Primera División | 08:00 |
| Diriangén | 1:0 | San Marcos de Huari | Nicaragua Primera Division | 08:00 |